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What happens if urine backs up into the kidneys?

Published in Kidney Health 4 mins read

If urine backs up into the kidneys, it leads to a condition called hydronephrosis, where one or both kidneys become stretched and swollen due to the accumulation of urine inside them. This build-up prevents the kidneys from draining properly, which can have significant health consequences if left untreated.


Understanding Hydronephrosis: When Urine Backs Up

Hydronephrosis signifies that there's an obstruction or a functional problem preventing urine from flowing out of the kidney and down the ureter (the tube connecting the kidney to the bladder). This can affect people of any age, and is sometimes identified in unborn babies during routine pregnancy ultrasound scans, a condition known as antenatal hydronephrosis.

Why Does Urine Back Up?

The backward flow or blockage of urine typically occurs due to an obstruction somewhere along the urinary tract, from the kidneys down to the urethra. Common causes include:

  • Kidney Stones: These hard mineral deposits can block the ureters, preventing urine flow.
  • Enlarged Prostate (BPH): In men, an enlarged prostate gland can compress the urethra, making it difficult for urine to exit the bladder, which can then cause urine to back up into the kidneys.
  • Tumors: Growths in or near the urinary tract (e.g., bladder, prostate, uterus, colon) can press on the ureters and obstruct urine flow.
  • Blood Clots: Clots in the urinary tract can create blockages.
  • Strictures: Narrowing of the ureters, often due to injury, infection, or previous surgery, can impede urine passage.
  • Nerve Damage: Conditions affecting nerves that control bladder function (e.g., spinal cord injury, diabetes) can lead to urine retention and backup.
  • Vesicoureteral Reflux (VUR): A condition where urine flows backward from the bladder into the ureters and kidneys. This is more common in children.

Symptoms of Urine Backup

The symptoms of hydronephrosis can vary depending on the cause, the extent of the blockage, and whether it's acute (sudden) or chronic (gradual).

  • Pain: Often experienced in the back or side (flank pain), which can be dull and aching or sharp and severe if caused by a kidney stone.
  • Urinary Changes:
    • Increased urge to urinate
    • Frequent urination
    • Painful urination (dysuria)
    • Difficulty emptying the bladder completely
  • Nausea and Vomiting: Especially with acute severe blockages.
  • Fever and Chills: If an infection develops in the backed-up urine.
  • Abdominal Swelling: In some cases, the abdomen might appear swollen.

The Consequences of Untreated Hydronephrosis

When urine backs up, the increased pressure within the kidney can damage the delicate filtering units (nephrons) over time. If left unaddressed, the potential complications include:

  1. Kidney Damage: Prolonged pressure can cause the kidney tissue to scar and lose its ability to filter waste products from the blood effectively.
  2. Kidney Failure: In severe cases, especially if both kidneys are affected or a single functioning kidney is blocked, it can lead to complete loss of kidney function, requiring dialysis or a kidney transplant.
  3. Kidney Infection (Pyelonephritis): Stagnant urine in the kidney provides a breeding ground for bacteria, leading to serious infections that can spread to the bloodstream (sepsis) if not treated promptly.
  4. High Blood Pressure: Chronic kidney issues, including those caused by hydronephrosis, can contribute to hypertension.

Diagnosis and Treatment

  • Diagnosis: Hydronephrosis is often diagnosed using imaging tests such as:
    • Ultrasound: A non-invasive method often used first, especially during pregnancy or in children.
    • CT Scan: Provides detailed images of the urinary tract.
    • MRI Scan: Can be used if other imaging is inconclusive or not suitable.
    • Cystoscopy: A thin, lighted tube is inserted into the urethra to examine the bladder and urethra.
  • Treatment: The primary goal of treatment is to relieve the blockage and restore normal urine flow. This typically involves addressing the underlying cause.
    • Draining Urine: A temporary measure might involve inserting a stent (a small tube) into the ureter or a nephrostomy tube through the back into the kidney to drain urine directly.
    • Treating Kidney Stones: Methods include shock wave lithotripsy (SWL), ureteroscopy, or percutaneous nephrolithotomy.
    • Managing Enlarged Prostate: Medications or surgical procedures (e.g., TURP) can relieve pressure on the urethra.
    • Surgery: To remove tumors, repair strictures, or correct anatomical abnormalities.
    • Antibiotics: To treat or prevent urinary tract infections.

Early diagnosis and treatment are crucial to prevent permanent kidney damage and other severe complications associated with urine backing up into the kidneys.