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What is ACI Knee Surgery?

Published in Knee Surgery 2 mins read

ACI knee surgery, or Autologous Chondrocyte Implantation, is a procedure to repair damaged cartilage in the knee. It involves growing a patient's own cartilage cells and then implanting them into the damaged area.

Understanding ACI Procedure

The ACI procedure is a two-step process:

  1. Cartilage Cell Collection:
    • A small sample of healthy cartilage cells (chondrocytes) is taken from the patient’s knee during an initial arthroscopic procedure.
  2. Cell Multiplication:
    • These cells are then sent to a laboratory where they are grown and multiplied to increase the cell number over approximately four weeks.
  3. Implantation:
    • The multiplied cells are then surgically implanted into the damaged area of the knee through a special technique.

Key Aspects of ACI

  • Autologous: The term "autologous" means the cells come from the patient's own body, reducing the risk of rejection.
  • Chondrocytes: These are the specialized cells responsible for maintaining cartilage health.
  • Cartilage Repair: This surgery aims to restore the smooth cartilage surface of the knee, reducing pain and improving mobility.
  • Two-Step Procedure: ACI involves an initial cartilage collection and a second implant procedure, usually separated by about four weeks to allow for cell multiplication.

Benefits of ACI

  • Cartilage Regeneration: ACI can regenerate new cartilage, which differs from procedures that only address symptoms.
  • Improved Knee Function: By restoring damaged cartilage, ACI can reduce pain and improve knee function.
  • Reduced Risk of Rejection: Since the cells come from the patient's body, there's a reduced risk of immune rejection.
  • Alternative for Younger Patients: ACI is often considered for younger, more active patients with specific types of cartilage damage.

Limitations of ACI

  • Two-stage Procedure: ACI involves two separate surgeries, which can be a disadvantage for some patients.
  • Recovery Period: Recovery after ACI can take several months and usually involves a structured rehabilitation program.
  • Not Suitable for All Cartilage Problems: ACI is typically recommended for focal cartilage defects and may not be suitable for generalized osteoarthritis.
Feature Description
Definition Autologous Chondrocyte Implantation
Cells Used Patient’s own cartilage cells (chondrocytes)
Procedure Steps Collection, Multiplication, Implantation
Goal Repair damaged cartilage in the knee
Recovery Can take several months with structured rehabilitation
Risk of Rejection Low, as cells are autologous