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Does Fever Affect the Liver?

Published in Liver and Fever 2 mins read

Yes, fever can affect the liver, especially in the context of certain infections.

Many viral infections that cause fever can also impact the liver. According to the provided reference, viral hemorrhagic fevers are a group of illnesses that "cause rather similar liver pathology." These fevers often involve damage to small blood vessels in multiple organs, which can include the liver.

How Fever-Related Illnesses Impact the Liver

While fever itself is a symptom, the underlying causes of fever, particularly viral infections, can directly affect liver function. Here's how:

  • Direct Viral Damage: Certain viruses directly infect liver cells (hepatocytes), leading to inflammation and damage.
  • Immune Response: The body's immune response to the infection can also contribute to liver damage. As the immune system fights the virus, it can cause inflammation that affects liver function.
  • Hemorrhage: As highlighted by the reference, viral hemorrhagic fevers can cause damage to small vessels, leading to bleeding and dysfunction in organs like the liver.

Examples of Fever-Causing Illnesses that Affect the Liver

Some examples of viral infections known to cause both fever and liver involvement include:

  • Viral Hepatitis: Hepatitis A, B, C, D, and E can all cause fever along with liver inflammation.
  • Yellow Fever: As the name implies, this viral disease transmitted by mosquitoes can lead to fever and jaundice, indicating liver damage.
  • Ebola and Marburg: These are viral hemorrhagic fevers known to severely affect the liver, among other organs.