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What is Sperm Infection?

Published in Male Reproductive Health 2 mins read

Sperm infection, also known as pyospermia or leukocytospermia, refers to the presence of a high number of white blood cells in semen. This indicates an infection somewhere in the male reproductive tract. The infection itself can weaken sperm cells, damage their genetic material, and significantly impact fertility. Several factors can contribute to a sperm infection, including bacterial infections, such as Escherichia coli (a common bacteria found in the gut), and viral infections like HIV, HBV, and HCV. These infections can reduce sperm motility (movement), affect DNA integrity, and lower overall sperm count. Inflammation of the seminal vesicles or blockages in the vas deferens can also contribute. Symptoms vary depending on the underlying cause, but a semen analysis revealing a high white blood cell count is a key indicator. Diagnosis is typically performed by a urologist or a specialist in male reproductive health. Treatment often involves antibiotics for bacterial infections and managing underlying health conditions.

Understanding Sperm Infections: A Deeper Dive

Several factors can lead to a sperm infection:

  • Bacterial Infections: These are common causes and can be treated with antibiotics. E. coli is frequently identified.
  • Viral Infections: Viruses like HIV, HBV, and HCV can be present in semen and negatively impact sperm health.
  • Inflammation: Inflammation of the seminal vesicles or prostate can increase white blood cell presence.
  • Blockages: Obstructions in the vas deferens (tubes that carry sperm) can create a breeding ground for infection.
  • Other Factors: Hormonal imbalances and chromosomal abnormalities are also linked in some cases.

Key Characteristics of Sperm Infection:

  • High White Blood Cell Count: A semen analysis is crucial for diagnosis, showing an unusually high number of white blood cells (leukocytes). This is the defining characteristic of pyospermia/leukocytospermia. A count exceeding 1 million white blood cells per milliliter of ejaculate often indicates infection.
  • Impact on Fertility: The infection can damage sperm DNA, reduce motility, and decrease sperm count, significantly affecting fertility.
  • Symptoms: Symptoms vary widely and may include pain, swelling, or discomfort in the testicles, penis, or groin area. However, many men with sperm infections may have no noticeable symptoms.

Diagnosis and Treatment:

Diagnosis relies primarily on a semen analysis. Treatment varies based on the identified cause, ranging from antibiotics for bacterial infections to managing underlying health conditions. Infertility treatments may be necessary if fertility is affected.