The full form of AHG is Antihuman Globulin.
Antihuman Globulin (AHG) is an antibody designed to react with human immunoglobulins (antibodies) and/or complement proteins. According to the reference provided, these antibodies are specifically targeted against the Fc portion of human antibodies, as well as complement components.
Here’s a breakdown of the key points regarding AHG:
- What it is: AHG is an antibody, meaning it is a protein produced by the immune system.
- What it Targets: AHG targets the Fc portion of human antibodies and/or complement components. The Fc portion is the tail end of an antibody molecule, responsible for interacting with other immune system components.
- Use in Medical Testing: AHG is crucial in various medical tests, primarily in blood banking and immunohematology, such as the Coombs test.
- Direct Coombs test : Detects antibodies or complement proteins that are already attached to red blood cells.
- Indirect Coombs test: Detects free-floating antibodies in the serum of an individual that are capable of reacting with red blood cells.
In summary, AHG is a vital reagent for detecting antibodies bound to red blood cells and assessing immune-mediated hemolytic conditions, among other applications.
