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What is the full form of VAPP?

Published in Medical Abbreviations 2 mins read

The full form of VAPP is Vaccine-associated paralytic poliomyelitis.

Understanding VAPP

VAPP is an adverse event that can occur following exposure to the oral polio vaccine (OPV). This vaccine utilizes a live, attenuated (weakened) version of the poliovirus to stimulate an immune response. While generally safe, in very rare instances, the weakened virus can revert to a more virulent form, leading to paralysis.

Key aspects of VAPP:

  • Cause: Arises from the live attenuated poliovirus in OPV.
  • Adverse event: Represents an unfavorable reaction linked to the vaccination.
  • Paralysis: A primary symptom involving muscle weakness and potential disability.
  • Rarity: VAPP is considered a very rare occurrence, much less common than naturally occurring polio.
  • OPV related: Specifically associated with oral polio vaccine and not with inactivated polio vaccine (IPV).

Why is it Important to Understand VAPP?

Despite its rarity, understanding VAPP is crucial for several reasons:

  1. Vaccine Safety: Ensures transparency about potential risks associated with vaccines, even if rare.
  2. Public Health: Informs vaccine policy decisions.
  3. Medical understanding: Helps doctors to diagnose and treat adverse reactions.
  4. Informed Consent: Allows medical professionals and patients to make informed choices.


Abbreviation Full Form Description
VAPP Vaccine-associated paralytic poliomyelitis An adverse reaction to OPV, resulting in paralysis in rare instances.


It's essential to remember that while VAPP is a recognized risk associated with OPV, the benefits of vaccination in preventing widespread polio outbreaks significantly outweigh the rare potential for adverse events.