Gullner syndrome is a rare, familial form of hypokalemia, characterized by low potassium levels in the blood. It was first identified in the 1970s when two brothers were diagnosed with this condition.
Key Features of Gullner Syndrome
- Familial Nature: This is a genetic condition, as evidenced by multiple siblings in the same family being affected.
- Hypokalemia: The primary characteristic is a significant reduction in potassium levels.
- Elevated Renin: Patients often have increased levels of renin, a hormone that regulates blood pressure.
Symptoms
The two brothers initially diagnosed with Gullner syndrome experienced:
- Fatigue
- Muscle cramps
Table Summary of Gullner Syndrome
| Feature | Description |
|---|---|
| Type | Familial hypokalemia |
| Discovery | 1970s in two brothers |
| Key finding | Low potassium levels (hypokalemia) |
| Hormonal Imbalance | Increased renin levels |
| Symptoms | Fatigue, muscle cramps |
| Reference: | First described in the 1970s; 3 additional siblings were found to have elevated renin and decreased potassium levels |
Gullner syndrome is not as common, with limited number of cases reported. It's crucial for those with a family history of hypokalemia and associated symptoms to seek appropriate medical consultation for proper diagnosis and management.
