Based on the provided reference, "treacle syndrome" appears to be a misspelling or misunderstanding of Treacher Collins Syndrome (TCS).
Here's a breakdown of Treacher Collins Syndrome:
Treacher Collins syndrome (TCS) is a genetic disorder characterized by distinctive facial abnormalities. These abnormalities result from problems with the development of certain bones and tissues in the face.
Key characteristics of Treacher Collins Syndrome (TCS):
- Lower Eyelid Abnormalities: Issues with the structure and function of the lower eyelids.
- Malar Hypoplasia: Underdevelopment of the cheekbones (malar bones), leading to a flattened facial appearance.
- Downslanted Palpebral Fissures: The opening between the eyelids (palpebral fissure) has a downward slant.
- Micrognathia or Retrognathia: A small or recessed lower jaw (mandible), contributing to a receding chin.
- Symmetric Hypoplasia: These abnormalities, including those affecting the zygomatic bones (cheekbones), maxilla (upper jaw), and mandible (lower jaw), occur symmetrically on both sides of the face.
Therefore, it's likely that "treacle syndrome" is a misspelling or alternate name for Treacher Collins Syndrome, which involves the aforementioned facial abnormalities stemming from hypoplasia of facial bones.
