zaro

What is the difference between ischemia and infarction?

Published in Medical Pathology 1 min read

Ischemia and infarction are related conditions affecting blood flow to tissues, but they differ in severity and outcome.

Understanding Ischemia

Ischemia refers to a decrease in blood flow to a tissue, leading to a shortage of oxygen. According to the provided reference, this oxygen shortage is called hypoxia.

Understanding Infarction

Infarction, on the other hand, represents a more severe condition. It occurs when blood flow to a tissue is completely cut off. The reference highlights that this total blockage results in necrosis, which is cell death.

Ischemia vs. Infarction: Key Differences

The primary distinction lies in the degree of blood flow restriction and its consequences:

Feature Ischemia Infarction
Blood Flow Decreased blood flow (hypoxia) Completely cut off blood flow (necrosis)
Tissue Damage Potential for reversible damage Irreversible tissue death
Outcome Tissue dysfunction, but potentially recovery Tissue death, loss of function

In simpler terms: Ischemia is like having a partially blocked pipe, while infarction is like having the pipe completely blocked off.