The full form of MACI® is Matrix-induced Autologous Chondrocyte Implantation.
MACI® is a procedure used to treat cartilage damage in the knee. Let's break down what each part of the acronym means:
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Matrix-induced: This refers to the use of a collagen scaffold or membrane (the "matrix") to support the growth and development of cartilage cells.
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Autologous: This means the cells used in the procedure are taken from the patient's own body, reducing the risk of rejection. Specifically, chondrocytes (cartilage cells) are harvested from a healthy area of the patient's knee.
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Chondrocyte: These are the cells that produce and maintain cartilage, the tissue that cushions the joints.
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Implantation: This refers to the surgical process of placing the matrix, now populated with the patient's own chondrocytes, into the damaged area of the knee to promote cartilage regeneration.
Therefore, MACI is a type of regenerative medicine that uses the patient's own cells and a supporting matrix to repair damaged cartilage in the knee. It's considered a minimally invasive option compared to some other cartilage repair techniques.