Yes, montelukast may increase certain white blood cells, specifically eosinophils.
Montelukast and White Blood Cell Changes
Montelukast, a medication often prescribed for asthma and allergies, can sometimes affect white blood cell counts. The provided reference clearly states that montelukast may lead to an increase in particular white blood cells called eosinophils.
Eosinophils and Montelukast
- Eosinophils are a type of white blood cell involved in the immune response.
- An increase in eosinophils due to montelukast is a potential side effect.
- This increase is specifically mentioned in the context of patients with asthma and those taking or reducing oral steroid medications.
Churg-Strauss Syndrome
- The reference also notes that montelukast may be associated with Churg-Strauss syndrome, a rare blood vessel disease.
- Churg-Strauss Syndrome is often linked to an increase in eosinophil counts.
- This condition typically appears in patients with a history of asthma, particularly when discontinuing or lowering their oral steroid dosage.
Summary of Montelukast and WBC
| Effect | Description |
|---|---|
| Increased WBCs | Montelukast may lead to increased eosinophils, a type of white blood cell. |
| Churg-Strauss Syndrome | A rare blood vessel disease associated with montelukast, often seen in patients reducing oral steroids, may also present with increased eosinophils. |
In conclusion, while not a universal effect, montelukast can increase certain white blood cells, especially eosinophils, and this is especially noted in asthmatic patients or those changing their steroid treatment.
