The most frequently prescribed and generally considered gold standard treatment for melasma, especially the epidermal type, is hydroquinone (HQ).
Hydroquinone (HQ) for Melasma Treatment
Hydroquinone is a depigmenting agent commonly used in concentrations ranging from 2% to 5%, typically applied once daily.
Here's a breakdown of HQ's role:
- Mechanism of Action: HQ works by inhibiting tyrosinase, an enzyme crucial in melanin production. Melanin is the pigment responsible for the dark patches in melasma.
- Concentration: Formulations range from 2% to 5%. It's essential to follow a dermatologist's guidance on the appropriate concentration for your skin.
- Application: Usually applied once daily, often at night.
- Efficacy: Considered the "gold standard," HQ has a long track record of effectively lightening melasma.
