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What is NHC in biology?

Published in Molecular Biology 1 min read

NHC in biology refers to Non-Histone Chromosomal Protein.

Understanding Non-Histone Chromosomal Proteins (NHC)

Non-histone chromosomal proteins (NHC) are a diverse group of proteins found in eukaryotes that associate with chromosomes but are not histones. They play crucial roles in various cellular processes.

Key Functions of NHC:

According to the provided reference, NHCs are involved in:

  • Regulating nucleosome remodeling: They help in altering the structure of chromatin, making DNA more or less accessible for various processes.
  • Facilitating DNA replication: NHCs assist in the accurate duplication of the genetic material.
  • Supporting RNA synthesis: They play a role in transcription, the process of creating RNA from a DNA template.
  • Controlling histone gene expression: NHCs influence the production of histones themselves.

Importance of NHC:

NHCs are vital for maintaining the structural integrity of chromosomes and for regulating gene expression. They contribute to the complexity and dynamic nature of the eukaryotic genome.