No, mosquito blood itself is not poisonous. The danger lies not in the blood the mosquito takes, but in what the mosquito might transmit through its bite.
Understanding Mosquito Bites and Disease Transmission
Female mosquitoes bite humans to obtain blood for egg production. While the mosquito's saliva can cause irritation and itching at the bite site, the blood it ingests is not inherently toxic to humans. However, the real concern is the potential transmission of diseases. A mosquito can carry pathogens in its saliva or blood, such as those causing malaria (as noted in one of the provided references). This reference highlights the danger of certain mosquito bites carrying diseases like malaria.
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Disease Transmission: The danger associated with mosquito bites stems from the potential transmission of diseases like malaria, not from the blood itself. A mosquito that has previously fed on an infected individual can transmit the disease to a new host. The cited research on toxic effects in male mosquitoes focuses on the effect of blood feeding on their survival, not on its effect on humans. (Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC4726748/)
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Mosquito Saliva: It's the mosquito's saliva, injected during the biting process, that causes the itching and swelling, not the human blood it consumes. The body's reaction to this saliva is what creates the characteristic bump. (Source: https://www.cdc.gov/mosquitoes/about/about-mosquito-bites.html)
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Blood as a Vector: While blood can be a vector for disease, the mosquito is the primary carrier and transmitter of pathogens in the case of mosquito-borne illnesses. Simply getting a mosquito's blood on your skin is not a transmission route, unless it contains pathogens that can enter through a wound. (Source: https://www.quora.com/I-killed-a-mosquito-and-got-blood-on-my-hand-Is-it-possible-to-transmit-a-disease-from-human-to-human-through-blood-taken-by-a-mosquito)
Conclusion
Mosquito blood itself is not poisonous to humans. The risks associated with mosquitoes stem from the potential transmission of diseases through their saliva and the pathogens they might carry.