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What is GLS disease?

Published in Multiple Medical Conditions 2 mins read

"GLS disease" can refer to several different conditions, depending on the context.

1. Gray Leaf Spot (GLS) in Corn:

This is a fungal disease affecting corn crops, caused by the fungus Cercospora zeae-maydis. GLS can occur almost every growing season, and if conditions are favorable, it can cause significant economic losses in corn-producing regions. [1, 5]

2. GLS (Glutaminase) Gene Mutations:

This refers to genetic disorders caused by mutations in the GLS gene. The GLS gene codes for the enzyme glutaminase, which plays a crucial role in brain and kidney function. Mutations in this gene can lead to various health problems, including autosomal recessive spastic ataxia and optic atrophy. [2, 4, 6]

3. Left Ventricular Global Longitudinal Strain (GLS):

This is a measure of the strain or deformation of the left ventricle of the heart during contraction. It's a sensitive indicator of heart function and can be used to diagnose and monitor various heart conditions, including heart failure, chronic kidney disease, and hypertension. [3, 7, 8, 9, 10]

4. GLS-1027:

This is a drug currently being investigated as a potential treatment for canine inflammatory bowel disease (IBD). In rodent models, GLS-1027 has demonstrated the ability to modulate inflammation in autoimmune and inflammatory diseases. [11]

To understand "GLS disease" better, it's important to consider the specific context and the source of the information.