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What is a meningeal cyst?

Published in Neurological Condition 3 mins read

A meningeal cyst is an abnormal sac-like formation that develops from the protective membranes surrounding the brain and spinal cord. These cysts are essentially outpouchings or diverticula of the dura mater, arachnoid membrane, or nerve root sheath, leading to an accumulation of cerebrospinal fluid (CSF) in the extradural space.


Understanding Meningeal Cysts

A meningeal cyst, often referred to by various names such as an arachnoid cyst, perineural cyst (Tarlov cyst), or dural ectasia, represents a type of fluid-filled sac. They are characterized by their origin and contents:

  • Origin: They arise as diverticula (small, pouch-like protrusions) from one of the meningeal layers—specifically the dura mater (the tough outer membrane), the arachnoid (the delicate middle membrane), or the sheath surrounding a nerve root.
  • Contents: These cysts are filled with cerebrospinal fluid (CSF), the clear, watery fluid that normally cushions the brain and spinal cord, providing nutrients and removing waste.
  • Location: The CSF accumulates in the extradural space, meaning the fluid collects outside the outermost protective layer of the spinal cord or brain.

Key Characteristics

Understanding the nature of meningeal cysts involves recognizing their primary features:

  • Formation: They are formed when a small tear, defect, or weakness in the meningeal lining allows CSF to leak out and collect in a localized sac.
  • Fluid Composition: The fluid within these cysts is identical to the cerebrospinal fluid circulating throughout the central nervous system.
  • Variability: They can vary significantly in size, from very small and asymptomatic to large enough to exert pressure on adjacent nerves or structures.
  • Common Locations: While they can occur anywhere along the spinal column or around the brain, common sites include the thoracic, lumbar, or sacral regions of the spine.

Types of Meningeal Cysts

While often grouped under the general term "meningeal cyst," specific types are recognized based on their exact origin and characteristics:

  • Arachnoid Cysts: These are common and are formed within the arachnoid membrane. They typically do not involve the nerve root sheath.
  • Perineural Cysts (Tarlov Cysts): These specifically involve the nerve root sheath, often forming near the dorsal root ganglia (collections of nerve cells) and typically found in the sacral region of the spine.
  • Dural Ectasia: While not a true cyst, dural ectasia involves the widening or ballooning of the dural sac, which can sometimes lead to diverticula or cyst-like formations. It is often associated with connective tissue disorders.
Type of Cyst Primary Origin Typical Contents Common Location
Arachnoid Cyst Arachnoid membrane Cerebrospinal Fluid (CSF) Brain or Spinal Cord
Perineural Cyst Nerve root sheath (often dorsal root ganglion) Cerebrospinal Fluid (CSF) Sacral Spine
(Dural Diverticula) Dura mater Cerebrospinal Fluid (CSF) Spinal Cord (extradural space)

Symptoms and Diagnosis

Many meningeal cysts are discovered incidentally during imaging for unrelated conditions, as they often remain asymptomatic. However, when they grow large enough to compress nerves or surrounding tissues, they can cause symptoms such as:

  • Back pain or leg pain
  • Weakness or numbness
  • Bowel or bladder dysfunction
  • Headaches (if intracranial)

Diagnosis typically involves imaging techniques such as Magnetic Resonance Imaging (MRI) of the brain or spine, which can clearly visualize the fluid-filled sacs.

For more information on anatomical structures, you can refer to resources on the meninges and cerebrospinal fluid.