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What is the difference between GBS and CIDP?

Published in Neurological Disorders 1 min read

The key difference between Guillain-Barré Syndrome (GBS) and Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) lies in the speed of onset and progression of the disease.

GBS vs. CIDP: A Comparison

Feature Guillain-Barré Syndrome (GBS) Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Onset Acute: Develops rapidly. Chronic: Develops slowly.
Progression Reaches maximum severity in less than 4 weeks. Reaches maximum severity typically in over 8 weeks.
Classification Classic acute autoimmune neuropathy. Classic chronic autoimmune neuropathy.

In essence, GBS presents much more acutely, reaching its most severe state in under 4 weeks, while CIDP develops more slowly and reaches its peak severity typically over 8 weeks, classifying them as acute and chronic autoimmune neuropathies respectively. This difference in the speed of progression is a primary factor in distinguishing between the two conditions.