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Is 80% Neutrophils Bad?

Published in Neutrophil Count 2 mins read

A neutrophil level of 80% is considered a significantly high percentage of total white blood cells and can indicate an underlying issue. While the provided reference primarily gives a normal range for the absolute count, a high percentage like 80% often results in an absolute count that exceeds typical normal limits.

Understanding neutrophil counts involves looking at both the percentage and the absolute number.

What Are Neutrophils?

Neutrophils are a type of white blood cell that plays a crucial role in your immune system, specifically in fighting off bacterial and fungal infections.

Normal Neutrophil Levels

According to the provided reference, a normal neutrophil level is generally between 2,500 and 7,000 neutrophils per microliter. This range refers to the absolute number of neutrophils in a specific volume of blood.

The reference also mentions that a low neutrophil level is considered less than 45% of your total white blood cells or less than 1,500 neutrophils per microliter.

Summary of Reference Information:

Measure Level Reference Status
Absolute Count 2,500-7,000 Normal Range
Absolute Count < 1,500 Low Level
Percentage < 45% Low Level
Percentage 80% Question Level

Note: The reference does not explicitly state a normal percentage range or a threshold for a high level (percentage or absolute).

Why 80% Neutrophils Can Be Concerning

While the reference doesn't define a "high" percentage, 80% is well above the low threshold (<45%). The percentage of neutrophils is part of a differential white blood cell count, showing the proportion of each type of WBC.

To determine if 80% neutrophils is "bad" in terms of being outside the normal absolute range provided (2,500-7,000), the total white blood cell (WBC) count is needed.

  • Calculation: Absolute Neutrophil Count = (Neutrophil Percentage / 100) * Total WBC Count

If your total WBC count is within a typical range (e.g., 4,000-11,000 per microliter), 80% neutrophils would likely result in an absolute count near or above the upper limit of the normal range (7,000 per microliter) stated in the reference.

  • Example: If Total WBC Count = 9,000/μL, then 80% Neutrophils = (80/100) * 9,000 = 7,200/μL. This is slightly above the 7,000/μL normal upper limit.
  • Example: If Total WBC Count = 10,000/μL, then 80% Neutrophils = (80/100) * 10,000 = 8,000/μL. This is clearly above the normal upper limit.

A neutrophil count above the normal range (known as neutrophilia) can indicate:

  • Infection (especially bacterial)
  • Inflammation
  • Stress
  • Certain medications
  • Other medical conditions

Therefore, while the reference doesn't explicitly label 80% as "bad," a high percentage like this strongly suggests the absolute neutrophil count is elevated beyond the typical normal range provided (2,500-7,000/μL), which warrants further investigation by a healthcare professional.