You should stop nintedanib treatment if you do not tolerate the 100 mg twice daily dose.
Based on the provided information, a key reason to discontinue treatment with nintedanib is if a patient experiences intolerance to the lower dose of the medication. Specifically, the reference states:
- Intolerance at 100 mg Twice Daily: If a patient cannot tolerate nintedanib when taking the 100 mg dose twice per day, the treatment should be stopped.
Managing Missed Doses (Not a reason to stop)
It's important to note that missing a dose is handled differently and is not a reason to stop treatment entirely. If a dose is missed:
- Do not take an extra dose.
- Resume the medication at the next scheduled time with the recommended dose.
This guidance focuses specifically on when to discontinue the treatment permanently due to an inability to tolerate the medication at a particular dosage level.
