In ophthalmology, PFR stands for Post-fever Retinitis, an eye condition characterized by inflammation of the retina that typically emerges after a period of fever.
Understanding PFR in Ophthalmology
Post-fever retinitis (PFR) is defined as an infectious or para-infectious uveitic entity. This means it is an inflammatory condition affecting the uvea (the middle layer of the eye, which includes the iris, ciliary body, and choroid) and, specifically, the retina. It is triggered by either direct infection or an immune response that occurs subsequent to an infection.
Key Characteristics of PFR
- Nature: PFR is classified as an infectious or para-infectious uveitic entity. This dual classification highlights that it can result directly from an active infection within the eye or indirectly as a consequence of the body's immune reaction following a systemic infection.
- Causative Agents: The condition is attributed to several viral or bacterial agents. This indicates a broad range of potential pathogens that can lead to PFR.
- Geographical Prevalence: PFR is commonly seen in tropical countries. This suggests an association with infectious diseases more prevalent in these regions.
- Onset of Ocular Manifestations: The eye-related symptoms and signs typically begin to develop within days to weeks after the onset of the initial febrile illness. This post-fever timing is a defining feature of the condition, distinguishing it from other forms of retinitis that may occur concurrently with fever.
In essence, PFR is a specific type of retinal inflammation that clinicians look for when a patient presents with visual disturbances or eye pain following a recent febrile illness, especially in regions where certain viral and bacterial infections are common.
