In ophthalmology, DFP stands for DI-ISOPROPYL fluorophosphate. It is a substance that has been historically studied and utilized for its significant effects on the eye.
Key Characteristics and Effects of DFP in Ocular Health
DI-ISOPROPYL fluorophosphate (DFP) is primarily known for its potent pharmacological actions within the eye, making it relevant in the context of certain eye conditions. The reference explicitly highlights two critical effects:
- Marked and Prolonged Miotic Effect: DFP has been shown to cause a significant and long-lasting constriction of the pupil. Miosis is the medical term for pupil constriction.
- Lowering Intraocular Tension: Beyond its miotic action, DFP has also demonstrated the ability to reduce intraocular pressure (IOP) within the eye. This effect is particularly significant, as elevated IOP is a primary risk factor for conditions like glaucoma.
These effects have been observed in both normal eyes and specifically in glaucomatous eyes, indicating its potential therapeutic value in managing ocular conditions characterized by high intraocular pressure or requiring pupil constriction.
For a clearer overview, here's a summary of DFP's properties in ophthalmology:
| Property | Description |
|---|---|
| Full Name | DI-ISOPROPRYL fluorophosphate |
| Primary Ocular Effect | Marked and prolonged miotic effect (pupil constriction) |
| Secondary Ocular Effect | Lowers intraocular tension (intraocular pressure) |
| Observed In | Normal eyes and glaucomatous eyes |
Understanding DFP's role helps in comprehending historical pharmacological approaches to managing eye conditions like glaucoma, where controlling intraocular pressure and pupil dynamics is crucial.
