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What is the Weight of the Liver?

Published in Organ Weight 2 mins read

The weight of a human liver varies, but it typically ranges from approximately 968 to 1860 grams.

Factors Influencing Liver Weight

Several factors influence the exact weight of a liver:

  • Body Weight: Liver weight is correlated with overall body weight. Larger individuals tend to have heavier livers. A formula exists to estimate liver weight based on body weight and gender (Estimated standard liver weight (g) = 218 + BW (kg) x 12.3 + gender x 51).
  • Gender: Men generally have slightly heavier livers than women.
  • Individual Variation: Like most organs, there's natural variation in liver size and weight between individuals.
  • Health Conditions: Liver diseases and other health issues can affect liver size and weight.

Average Liver Weight

While individual variation exists, a commonly cited average weight for a human liver is around 1500 grams, representing roughly 2% of total body weight. This makes it the largest gland in the human body.

Liver Weight in Rodents

In rodent models, the average liver weight is considerably smaller, typically ranging from 2-3 grams in mice (3-5% of body weight) and 4-5 grams in rats (2-3% of body weight). This highlights the significant differences in organ size across species.

Importance of Liver Weight

Knowing the approximate weight of a liver is crucial for:

  • Medical Diagnostics: Deviation from the expected weight range can indicate underlying health problems.
  • Surgical Planning: Liver weight estimations are helpful in surgical procedures involving the liver.
  • Research: Consistent liver weight estimations are essential for preclinical research using animal models.

Conclusion

The human liver weighs approximately 968-1860 grams, with an average around 1500 grams. This weight is influenced by various factors, including body weight, gender, and health status.