The weight of a human liver varies, but it typically ranges from approximately 968 to 1860 grams.
Factors Influencing Liver Weight
Several factors influence the exact weight of a liver:
- Body Weight: Liver weight is correlated with overall body weight. Larger individuals tend to have heavier livers. A formula exists to estimate liver weight based on body weight and gender (Estimated standard liver weight (g) = 218 + BW (kg) x 12.3 + gender x 51).
- Gender: Men generally have slightly heavier livers than women.
- Individual Variation: Like most organs, there's natural variation in liver size and weight between individuals.
- Health Conditions: Liver diseases and other health issues can affect liver size and weight.
Average Liver Weight
While individual variation exists, a commonly cited average weight for a human liver is around 1500 grams, representing roughly 2% of total body weight. This makes it the largest gland in the human body.
Liver Weight in Rodents
In rodent models, the average liver weight is considerably smaller, typically ranging from 2-3 grams in mice (3-5% of body weight) and 4-5 grams in rats (2-3% of body weight). This highlights the significant differences in organ size across species.
Importance of Liver Weight
Knowing the approximate weight of a liver is crucial for:
- Medical Diagnostics: Deviation from the expected weight range can indicate underlying health problems.
- Surgical Planning: Liver weight estimations are helpful in surgical procedures involving the liver.
- Research: Consistent liver weight estimations are essential for preclinical research using animal models.
Conclusion
The human liver weighs approximately 968-1860 grams, with an average around 1500 grams. This weight is influenced by various factors, including body weight, gender, and health status.