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Is ATP a Vasodilator?

Published in Pharmacology & Physiology 1 min read

Yes, ATP is a vasodilator. According to the provided reference, ATP is a potent coronary vasodilator.

Here's a breakdown:

  • Vasodilator Definition: A vasodilator is a substance that causes blood vessels to widen, allowing for increased blood flow.

  • ATP's Role: The reference explicitly states that ATP acts as a vasodilator, specifically in the coronary arteries.

  • Clinical Application: The reference also mentions that ATP is safe for stress Cardiac Magnetic Resonance (CMR) imaging. Its vasodilatory effect is used to induce stress on the heart, allowing doctors to assess heart function under stress. The reference also states that the hyperemic response to ATP is quick and comparable to adenosine reported.

  • Splenic Switch-off: Splenic switch-off can serve as an indicator of stress success in ATP stress CMR.

Therefore, based on the provided reference, ATP functions as a vasodilator.