Yes, Polycythemia Vera (PV) can cause pain.
According to the reference, the pain associated with PV can arise from complications such as:
- Enlargement of the liver and spleen.
- Blood clots in the liver and spleen which can cause sudden, intense pain.
In summary, while PV itself might not always directly cause pain, complications arising from the condition, such as blood clots in the liver and spleen, can indeed lead to significant pain.