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What is an NT blood test?

Published in Prenatal Screening 2 mins read

An "NT blood test" is a misnomer; the NT (nuchal translucency) measurement is actually part of a sonogram or ultrasound, not a blood test. The ultrasound examines the fluid-filled space at the back of the fetal neck. However, blood tests are used in prenatal screening for similar purposes. Let's clarify both aspects:

Understanding the Nuchal Translucency (NT) Measurement

The nuchal translucency is the measurement of the clear (translucent) space in the tissue at the back of the fetus's neck. It is measured during a first-trimester ultrasound, typically between 11 and 14 weeks of pregnancy.

Key Points About the NT Measurement:

  • Sonogram, not a blood test: It's important to understand that NT measurement is obtained through an ultrasound, not a blood test.
  • What it measures: It looks for fluid accumulation at the back of the fetal neck.
  • When it's done: Typically performed during the first trimester of pregnancy, specifically between 11 and 14 weeks.
  • Purpose: It's part of combined screening that helps assess the risk of chromosomal abnormalities, like Down syndrome.

Blood Tests in First Trimester Screening

While NT is done via ultrasound, blood tests are a very important part of first-trimester screening. These blood tests analyze certain substances (analytes) in the mother's blood.

What Blood Tests Do:

  • Analyte Analysis: These tests examine various substances in the blood.
  • Risk Assessment: Combined with the NT measurement, these blood tests help to estimate the risk of chromosomal abnormalities.
  • Non-Invasive Prenatal Testing (NIPT): Newer methods like NIPT use blood tests to provide highly accurate results.
  • Ultrasound Still Recommended: Even with NIPT, a first-trimester ultrasound, including NT measurement, is still recommended.

Key Differences Summarized

Feature Nuchal Translucency (NT) First Trimester Blood Test
Method Ultrasound Sonogram Blood Test
Purpose Measures fluid at fetal neck Analyzes substances in blood
Typical Use Part of combined screening for chromosomal abnormalities. Helps in assessing risk of chromosomal issues.
Timing 11-14 weeks of pregnancy Can be done in the first trimester

Conclusion

The term "NT blood test" is not entirely accurate. While the NT measurement is part of an ultrasound, blood tests that analyze different substances in the blood are an important part of the first trimester prenatal screening process. These tests, when used alongside an NT ultrasound, assess risk of certain conditions. The development of NIPT (Noninvasive Prenatal Testing) has improved prenatal screening, using blood tests alone but the NT ultrasound remains a recommended practice.