A TPSA test, or Total Prostate Specific Antigen test, is a medical test primarily used to screen for issues concerning the prostate. It measures the total amount of a substance called Prostate Specific Antigen (PSA) in the blood.
Understanding PSA
Prostate Specific Antigen (PSA) is the key substance measured in a TPSA test. Based on the provided information:
- What it is: PSA is a type of protein known as a glycoprotein.
- Where it comes from: It is produced by specific cells in the prostate gland – namely, prostatic acinar cells and epithelial lining of the prostatic ducts.
- Specificity: PSA is specific to the prostate, meaning it is mainly found there.
- Cell Type: It can be expressed by both normal prostate cells and malignant (cancerous) prostate cells.
Purpose of the TPSA Test
As stated in the reference, TPSA testing is used primarily to screen for issues concerning the prostate. While PSA is produced by both normal and cancerous cells, levels can be elevated in various prostate conditions, including benign prostatic hyperplasia (BPH), prostatitis, and prostate cancer. Monitoring PSA levels over time is often part of prostate health evaluation, especially for men at risk for prostate cancer.
Key Points about TPSA Testing
- Measures total PSA levels in the blood.
- PSA is a glycoprotein specific to the prostate.
- Produced by prostatic acinar cells and duct lining.
- Expressed by normal and malignant prostate cells.
- Primarily used for screening prostate issues.
This test helps healthcare providers evaluate prostate health and determine if further investigation or monitoring is needed.
