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What is R in protein?

Published in Protein Chemistry 1 min read

In the context of proteins and amino acids, "R" refers to the R group, also known as a side chain. This side chain is unique to each of the 20 common amino acids and confers specific chemical properties to that amino acid (Reference: R group).

Understanding R Groups

  • Diversity: Each amino acid has a different R group.
  • Functionality: These R groups determine the amino acid's characteristics, such as whether it's polar, nonpolar, acidic, or basic.
  • Protein Structure: R groups play a crucial role in protein folding and overall protein structure, as interactions between different R groups influence how the protein twists and bends.

Examples of R Groups and their Properties

Amino Acid R Group Properties
Glycine -H Nonpolar
Alanine -CH3 Nonpolar
Serine -CH2OH Polar
Cysteine -CH2SH Polar
Aspartic Acid -CH2COOH Acidic
Lysine -(CH2)4NH2 Basic

The properties of these R groups influence how proteins interact with other molecules and carry out their functions.