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Is Keratin a Collagen?

Published in Protein Types 2 mins read

No, keratin is not collagen. While both are proteins crucial for bodily structure and function, they have distinct roles and compositions.

Key Differences Between Keratin and Collagen

  • Function: Collagen primarily provides structural support to the body, forming the connective tissues in skin, bones, and cartilage. Keratin's main role is protection, forming a hard, protective layer in skin, hair, and nails.

  • Production: Collagen is synthesized by fibroblast cells, whereas keratin is produced by keratinocytes.

  • Location: Collagen is a major component of connective tissues throughout the body. Keratin is the primary structural protein in hair, skin, and nails.

  • Structure and Properties: Collagen forms strong, flexible fibers, contributing to tissue strength and elasticity. Keratin forms strong, insoluble fibers, resulting in tough, protective structures. Collagen is a component of the hair shaft along with keratin.

Several sources confirm these differences. For example, this blog post highlights collagen's role in hair strength and structure alongside keratin. Another source (https://www.differencebetween.com/what-is-the-difference-between-collagen-and-keratin/) emphasizes collagen's dominance in connective tissues and keratin's presence in skin, hair, and nails. Further, a research article on scleroproteins (https://pubmed.ncbi.nlm.nih.gov/33344740/) places both proteins within this category but notes their distinct filamentous structures and functions.

In short, while both are essential proteins, keratin and collagen are distinct, with different structures, functions, and cellular origins. They often work together, as in the hair shaft, but are not interchangeable.