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What Drug is TM?

Published in Psychedelic Drugs 2 mins read

TM refers to Thiomescaline, a pair of lesser-known psychedelic drugs. Specifically, it encompasses two analogs of mescaline: 3-TM and 4-TM. These compounds are similar to mescaline but with a crucial difference: an oxygen atom has been replaced by a sulfur atom in their molecular structure.

Thiomescaline Details

  • Molecular Formula: C11H17NO2S
  • Type: Psychedelic drug, specifically a mescaline analog.
  • Forms: Exists as two isomers, 3-TM and 4-TM, differing in the sulfur atom's position on the aromatic ring.
  • Discovery: First synthesized by Alexander Shulgin.
  • Documentation: Described in Alexander Shulgin's book, PiHKAL: A Chemical Love Story.

3-TM and 4-TM: Variations of Thiomescaline

The distinction between 3-TM and 4-TM lies in the position of the sulfur atom on the benzene ring. This structural difference might lead to variations in their pharmacological effects, although detailed information about their individual effects is limited.

Alexander Shulgin and PiHKAL

Alexander Shulgin was a renowned chemist and pharmacologist known for synthesizing and documenting the effects of various psychoactive substances. PiHKAL (Phenethylamines I Have Known And Loved) is a book co-authored with his wife Ann Shulgin, detailing the synthesis, dosages, and effects of numerous phenethylamine compounds, including thiomescaline.

Importance of Context

It is important to note that due to the limited research and documentation on thiomescaline, the effects and risks associated with its use are not fully understood. Any use would carry significant risks.