Purdue has lost in the first round of the NCAA Tournament four times.
Purdue's NCAA Tournament First Round Exits
Under Coach Matt Painter, who took over in 2005, the Purdue Boilermakers have demonstrated significant success, making 15 NCAA Tournament appearances in 19 seasons. Despite this impressive consistency, the Boilermakers have been eliminated in the first round on four occasions during this span.
One of the most notable of these first-round exits occurred when Purdue, as a No. 1 seed, suffered an upset loss to No. 16 seed Fairleigh-Dickinson with a final score of 63-58. This game stands out as a significant moment in the program's recent tournament history.
For more details on Purdue men's basketball history, including their tournament performances, you can refer to reputable sports information sources such as USA Today.