Yes, Lizzie from the classic arcade game Rampage is unequivocally depicted as a female character.
Originally, Lizzie was a woman who underwent a terrifying transformation. Her mutation occurred after she came into contact with discarded radioactive waste while swimming in a lake. This exposure caused her to evolve into a colossal, monstrous lizard or dinosaur. She is one of the three primary colossal creatures players can control in the Rampage series, alongside her male counterparts:
- George: A giant ape, mutated from a human male.
- Ralph: A colossal werewolf, also mutated from a human male.
Lizzie's background as a human female before her monstrous transformation solidifies her identity as a girl, or more accurately, a woman, within the game's lore. Her character design and narrative origin consistently reflect her feminine identity, making her a unique and memorable member of the destructive trio in the Rampage universe.
