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What is RNA?

Published in RNA Biology 2 mins read

Do Humans Have RNA?

Yes, humans have RNA. In fact, the human genome contains at least 80,000 non-redundant non-coding RNA genes. This highlights RNA's crucial role in human biology, far beyond its involvement in protein synthesis.

Ribonucleic acid (RNA) is a nucleic acid found in all living cells. Similar in structure to DNA, RNA plays several vital roles:

  • Protein synthesis: RNA carries genetic information from DNA to ribosomes, where proteins are built. Messenger RNA (mRNA) is a key player in this process.
  • Gene regulation: Many types of RNA, including non-coding RNA, regulate gene expression, influencing which genes are turned on or off. This intricate control is essential for proper cellular function.
  • Other cellular processes: RNA participates in various other cellular processes, including RNA splicing, RNA editing, and more.

Types of RNA in Humans:

Humans possess several RNA types, each with unique functions:

  • mRNA (messenger RNA): Carries genetic instructions from DNA to ribosomes.
  • tRNA (transfer RNA): Brings amino acids to ribosomes during protein synthesis.
  • rRNA (ribosomal RNA): A major structural component of ribosomes.
  • snRNA (small nuclear RNA): Involved in RNA splicing.
  • miRNA (microRNA): Regulates gene expression by binding to mRNA.
  • And many more…: Thousands of other non-coding RNAs (ncRNAs) with diverse roles in gene regulation and other cellular processes.

The discovery of the vast number of non-coding RNA genes (at least 80,000) has revolutionized our understanding of the cell, leading researchers to call the eukaryotic cell an “RNA machine.” This emphasizes the pervasive and critical functions RNA performs beyond protein synthesis.

RNA's Significance in Human Health

The understanding of RNA's functions has opened up new avenues for therapeutic interventions. Researchers are exploring the potential of RNA-based therapies to treat various diseases, including cancer and genetic disorders. Specific RNA molecules can regulate gene expression and show promise as therapeutic agents.