What is CP skin disease?

Cicatricial pemphigoid (CP) is a group of rare, chronic blistering disorders that primarily affect the mucous membranes and sometimes the skin. It is a subepithelial blistering condition.

Understanding Cicatricial Pemphigoid

Cicatricial pemphigoid (CP) is not a single disease but rather a group of conditions that share similar characteristics. The primary feature of these conditions is the development of blisters beneath the surface layer of the skin (subepithelial). These blisters can occur in various locations, most commonly affecting the mucous membranes but sometimes impacting the skin itself.

Key Characteristics of CP

Here's a breakdown of what defines CP:

• Rare and Chronic: CP is not a common condition and tends to be long-lasting.
• Subepithelial Blistering: The blisters form in the tissue layer beneath the skin's surface.
• Affects Mucous Membranes: Frequently, CP impacts the linings of the mouth, eyes, and other moist tissues.
• Skin Involvement: While less common, the skin can also be affected.
• Potentially Serious: CP can lead to significant health issues and, in rare cases, can be fatal.

Common Clinical Features

The clinical presentation of CP can vary, but some features are often present:

• Desquamative Gingivitis: Red, inflamed gums that may peel or bleed.
• Oral Erosions: Sores or open areas in the mouth.
• Conjunctival Fibrosis: Scarring of the tissues in the eyes, which can cause vision problems.

Types of CP

While not detailed in the reference, CP can be further categorized based on the specific areas of the body affected and the types of tissues involved. However, the reference provided highlights that CP is a heterogeneous group.

Impact of CP

CP, as a group of disorders, can have a wide range of effects. Beyond the immediate discomfort of blisters and sores, CP can lead to:

• Vision Problems: Scarring of the eyes can lead to reduced vision and even blindness.
• Difficulty Eating: Oral lesions can make eating painful and difficult.
• General Discomfort: The chronic nature of the disease often leads to long-term discomfort and reduces quality of life.

Summary