OTB can stand for "off the board" in the context of sports betting.
OTB Meaning in Sports Betting
In sports betting, "OTB" or "off the board" indicates that a particular game's line is not currently available for betting. This can occur for several reasons, as explained below:
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Game Not Listed: The phrase "off the board” comes from the fact that if you are looking at a board with sports bets on it, the game's line would no longer be listed on the board.
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Unavailable Bets: Sometimes a game won't be listed for bets.
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Line Shown as "Off": Other times, the line will be shown as "off" or with the acronym OTB.