GUS treatment depends on the underlying cause of the genital ulcer syndrome (GUS). Based on the provided information, if the clinical presentation of GUS is herpes, the treatment is aciclovir. If certain risk factors and distinct syphilis clinical features are present, treatment should empirically be with benzathine benzylpenicillin for syphilis.
In essence, the approach hinges on diagnosing the specific cause of the genital ulcer. If herpes simplex virus is identified as the culprit, antiviral medication like aciclovir is used. If syphilis is suspected, especially in the presence of relevant risk factors or characteristic clinical signs, penicillin is administered.
Therefore, determining the etiology of the genital ulcer is paramount for choosing the correct treatment strategy.
