RDW (Red Cell Distribution Width) in thalassemia, specifically beta thalassemia trait, is typically normal or only mildly increased; it's a measure of anisocytosis.
Understanding RDW and Thalassemia
Here's a breakdown:
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RDW Defined: RDW measures the variation in the size of your red blood cells (anisocytosis). A high RDW means there's a significant difference in red blood cell sizes.
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Thalassemia Impact: In beta thalassemia trait, RDW is usually normal or only slightly elevated. This is unlike iron deficiency anemia, where RDW is characteristically increased.
RDW as a Differentiating Factor
- Distinguishing Beta Thalassemia Trait from Iron Deficiency Anemia: RDW can be used to help distinguish between beta thalassemia trait and iron deficiency anemia. A normal or mildly elevated RDW suggests beta thalassemia trait, while a high RDW suggests iron deficiency anemia. This is supported by research highlighting RDW as a valuable discrimination index.
RDW Value in Thalassemia
| Feature | RDW Value |
|---|---|
| Beta Thalassemia Trait | Normal or mildly increased |
| Definition | Measure of red blood cell size variation |
