The reference provided indicates that "Hh" in the context of tuberculosis (TB) treatment refers to Isoniazid - High dose.
Isoniazid (INH) is a crucial first-line antibiotic used to treat and prevent TB. It works by stopping the growth of the bacteria Mycobacterium tuberculosis, which causes the disease. The "Hh" designation signifies a higher dosage regimen of Isoniazid compared to standard doses.
While the specific dosage defining "high dose" can vary based on guidelines from organizations like the World Health Organization (WHO), local protocols, patient factors (e.g., weight, age, renal function), and the specific clinical situation (e.g., drug-resistant TB), it's generally understood that "Hh" implies a dosage exceeding the typical daily Isoniazid dose.
It's important to note that high-dose Isoniazid can increase the risk of side effects, such as liver toxicity and peripheral neuropathy. Therefore, patients receiving this regimen require careful monitoring by healthcare professionals.
