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What is desmoplasia?

Published in Tumor Biology 1 min read

Desmoplasia is the formation of connective tissue in response to tumors.

Understanding Desmoplasia

Desmoplasia, derived from the Greek words desmos, meaning “connective,” and plasia, meaning “formation,” refers to the growth of fibrous or connective tissue. Crucially, this process is often seen in the environment surrounding tumors. It's essentially a reaction of the body to the presence of cancerous cells.

Key Aspects of Desmoplasia:

  • Definition: Formation of connective tissue.
  • Trigger: Typically occurs in response to tumors.
  • Mechanism: The body's attempt to wall off or contain the tumor.

In essence, desmoplasia represents a complex interaction between tumor cells and the surrounding normal tissue, playing a significant role in tumor progression and response to therapy.