Type 2 Diabetes Mellitus (T2DM) is primarily caused by a combination of genetic and lifestyle factors that lead to insulin resistance and impaired insulin secretion.
Understanding the Causes
Several key factors contribute to the development of T2DM:
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Genetics: Genetic predisposition plays a significant role, increasing an individual's susceptibility to developing T2DM.
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Excess Body Fat: Specifically, having excess body fat, particularly visceral fat (belly fat around the organs), is strongly linked to insulin resistance.
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Physical Inactivity: A sedentary lifestyle reduces insulin sensitivity and increases the risk of developing T2DM.
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Diet: Consuming a diet frequently high in processed foods, carbohydrates, and saturated fats contributes to insulin resistance and weight gain, increasing the risk of T2DM.
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Medications: Certain medications, such as long-term corticosteroid use, can also increase the risk of developing T2DM.
In summary, T2DM is a complex condition influenced by a combination of genetic vulnerability and lifestyle choices. Addressing modifiable risk factors, such as diet and physical activity, can significantly reduce the risk of developing T2DM.
