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What is the difference between urine culture and urine culture and sensitivity?

Published in Urine Tests 2 mins read

The key difference between a urine culture and a urine culture and sensitivity lies in what each test assesses after a potential infection is detected.

Feature Urine Culture Urine Culture and Sensitivity
Primary Goal Detect and identify bacteria or yeasts in the urine. Detect and identify bacteria/yeasts and determine which antibiotics will inhibit their growth.
What it Determines Whether or not an infection (UTI) is present. Whether an infection is present and which antibiotics are most effective against the specific microbe.
Susceptibility Testing Not performed unless the culture is positive. Always performed if the culture is positive.
Reference Information Determines the bacteria or yeasts causing the infection (Reference). Determines which antibiotics will inhibit the growth of the microbe causing the infection (Reference).

Essentially, a urine culture is used, along with results from a urinalysis, to diagnose a UTI and identify the specific bacteria or yeasts causing the infection.

Urine culture and sensitivity takes it a step further. If the urine culture is positive (meaning bacteria or yeasts are present), a susceptibility test is performed to determine which antibiotics will be most effective in treating the infection by inhibiting the microbe's growth. This helps doctors choose the right antibiotic to prescribe.