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What is Rotavac vaccine?

Published in Vaccine Information 1 min read

Rotavac vaccine is a monovalent, liquid, frozen vaccine given orally to prevent rotavirus gastroenteritis, a common cause of severe diarrhea in infants and young children. This vaccine uses a live, weakened (attenuated) rotavirus strain.

Key Characteristics of Rotavac Vaccine

Here's a breakdown of what makes Rotavac a unique vaccine:

  • Type: Live attenuated oral vaccine
  • Strain: Contains a specific rotavirus strain, 116E
  • Production: Prepared in Vero cells
  • Formulation: Liquid and frozen
  • Dosage: Each 0.5 ml dose has at least 105.0 FFU (Fluorescent Focus Units) of live rotavirus 116E.
  • Purpose: To prevent rotavirus gastroenteritis

How Rotavac Works

Rotavac works by introducing a weakened form of the rotavirus into the body. This triggers an immune response, allowing the body to develop antibodies that will protect against future infections from the wild-type rotavirus.

Additional Insights

  • Administration: Since Rotavac is an oral vaccine, it is given as drops into the baby's mouth.
  • Storage: The liquid vaccine is stored frozen to maintain its potency.

Who Should Receive Rotavac?

Rotavac is primarily intended for infants and young children, who are most susceptible to rotavirus infections.