What Deficiency Causes Allergies?

A vitamin D deficiency is associated with an increased risk and worsening of allergies and allergic diseases like asthma. While not the sole cause, it's a significant contributing factor.

Studies have shown a strong correlation between vitamin D deficiency and the prevalence of allergic diseases. The increase in asthma and allergies observed over the past 50-60 years may be partly explained by widespread vitamin D deficiency. [^1, ^5] This deficiency can exacerbate allergic symptoms, as demonstrated in animal models of food allergies. [^2] Research consistently reveals a high prevalence of vitamin D deficiency in children with asthma and other allergic conditions. [^4, ^8] The severity of allergic rhinitis has also been linked to vitamin D levels. [^9] Even a specific instance connects vitamin D deficiency rickets with cow's milk allergy. [^10]

Furthermore, while not directly causing allergies, a deficiency in Immunoglobulin A (IgA) is linked to an increased likelihood of experiencing allergic reactions. [^7] However, it's important to note that IgA deficiency is a primary immune deficiency, meaning it's an inherent problem with the immune system. This is different from the secondary deficiency related to Vitamin D.

Important Note: Other factors contribute to the development of allergies. This information highlights a strong link between vitamin D deficiency and allergic reactions but doesn't suggest that deficiency is the only causative factor.

[^1]: Vitamin D deficiency is prevalent worldwide and may partly explain the increases in asthma and allergic diseases that have occurred over the last 50–60 years.
[^2]: Vitamin D deficiency has been shown to exacerbate sensitization and allergic symptoms in a murine model of food allergy.
[^4]: The study findings revealed a high prevalence of Vitamin D deficiency in children with asthma and allergic diseases.
[^5]: Vitamin D deficiency is prevalent worldwide and may partly explain the increases in asthma and allergic diseases that have occurred over the last 50–60 years.
[^7]: Some people with IgA deficiency also are more likely to have allergies.
[^8]: Vitamin D Deficiency Is Correlated with Severity of Allergic Rhinitis
[^9]: Vitamin D Deficiency Is Correlated with Severity of Allergic Rhinitis
[^10]: Milk allergy and vitamin D deficiency rickets: a common disorder