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Why is yellow fever vaccine not recommended for over 60?

Published in Yellow Fever Vaccine Safety 2 mins read

The yellow fever vaccine is generally not recommended for individuals over 60 primarily due to an increased risk of experiencing rare but serious side effects.

Increased Risk of Serious Side Effects for Older Adults

As individuals age, their immune systems can react differently to vaccines. For those over 60, there's a heightened susceptibility to specific adverse reactions following the yellow fever vaccination.

The most significant concern is the increased likelihood of developing Yellow Fever Vaccine-Associated Neurological Disease (YEL-AND). This rare but severe condition affects the brain and nervous system, leading to concerning symptoms.

  • Symptoms of YEL-AND can include:
    • Confusion: Disorientation and difficulty thinking clearly.
    • Problems with Movement: Impaired coordination and difficulty with motor skills.
    • Difficulties with Co-ordination: Trouble with balance and performing smooth, controlled actions.

These neurological complications can have a more profound impact on the health and recovery of older adults compared to younger individuals.

To illustrate the difference in risk:

Age Group Risk of Rare Side Effects (e.g., YEL-AND)
General Adult Lower
Over 60 Higher

Balancing Risk and Benefit

Healthcare professionals meticulously weigh the potential benefits of vaccination against the increased risks for individuals over 60. This decision considers factors such as:

  • Travel Destination: The actual risk of yellow fever transmission in the specific area the individual plans to visit.
  • Length of Stay: Longer stays in high-risk areas might slightly alter the risk assessment.
  • Individual Health Status: Pre-existing health conditions can further influence the vaccine's safety profile.

In many cases, if the risk of yellow fever exposure is low or moderate, the elevated risk of severe vaccine side effects for older adults often leads to a recommendation against the vaccine.

Consulting a Travel Health Expert

It is crucial for individuals over 60 who are considering travel to regions with yellow fever risk to consult with a travel health specialist or their doctor. These professionals can provide personalized advice by:

  • Assessing individual health conditions and medical history.
  • Evaluating the specific yellow fever risk of the travel itinerary.
  • Discussing alternative preventive measures, such as strict mosquito bite avoidance, if vaccination is deemed too risky.

For more detailed information on yellow fever vaccine recommendations and risks, you can refer to reputable travel health guidelines, such as those provided by Fit for Travel.